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KMID : 0357919880220020199
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Korean Journal of Pathology
1988 Volume.22 No. 2 p.199 ~ p.203
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Porencephaly -An Autopsy Case Report
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김인숙/In Sook Kim
손진희/박효숙/지제근/Jin Hee Shon/Hyo Sook Park/Je Geun Chi
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Abstract
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Porencephaly is a rare congenital anomaly characterized by a cavitary hole extending
from the cerebral mantle to the ventricle of the brain and covered by leptomeningeal
membrane. It is now generally believed that the porencephaly represents a fetal or
neonatal destructive process of the neural tissue.
Authors experienced an autopsy case of bilateral porencephaly in a 35-day-old Korean
male infant who died of sepsis. The brain weighed 150 ems and morphologically well
formed except for two large symmetric defects at the fronto-parietal region. These
defects were characterized by cleft-like shape, covering the entire cerebral mantle with
resultant direct communication between ventricular cavity and leptomeninges. Thin
leptomeningeal trabeculae were covering the cavity. There was a smooth transition
between ependyma and roof of the defects. There are focal, microscopic cerebral infarct
and abscess without connection with the cavitary lesion. The remaining central nervous
system was unremarkable.
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KEYWORD
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